So, coronavirus...

Where goats go to escape
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Raggs
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Biffer wrote: Thu Mar 18, 2021 10:41 am
Rinkals wrote: Thu Mar 18, 2021 10:27 am I'm talking about a "temporary moratorium".

Not cancelling the right to earn from your investment.
So you're expecting China and India to 'forget' the IP and never use it again after a couple of years? That would not happen. It's fairyland to think it would.
And we're talking mRNA tech here. Brand new, tons of issues with getting it to actually work, and once you have the equipment and know how, then... well... you've got the equipment and know how, even if they make you pinky promise not to use it...
Give a man a fire and he'll be warm for a day. Set a man on fire and he'll be warm for the rest of his life.
Biffer
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Raggs wrote: Thu Mar 18, 2021 10:46 am
Biffer wrote: Thu Mar 18, 2021 10:41 am
Rinkals wrote: Thu Mar 18, 2021 10:27 am I'm talking about a "temporary moratorium".

Not cancelling the right to earn from your investment.
So you're expecting China and India to 'forget' the IP and never use it again after a couple of years? That would not happen. It's fairyland to think it would.
And we're talking mRNA tech here. Brand new, tons of issues with getting it to actually work, and once you have the equipment and know how, then... well... you've got the equipment and know how, even if they make you pinky promise not to use it...
Exactly. India is the prime mover in challenging IP around medicine tech generally, to expect them not to continue to use it is complete nonsense.
And are there two g’s in Bugger Off?
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Saint
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In other good news, it looks like the Brazil variant is more susceptible to AZ and Pfizer than first thought - although not peer reviewed yet
Dinsdale Piranha
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Saint wrote: Thu Mar 18, 2021 12:23 pm In other good news, it looks like the Brazil variant is more susceptible to AZ and Pfizer than first thought - although not peer reviewed yet
I saw some analysis that said the initial reports were really pretty inaccurate - correct about the transmissibility but not about vaccine resistance - due to the people the analysis was based on - a similar issue to the SA variant reporting.

On another note the USA stockpiling AZ makes me think it will be approved pretty soon.

Got my first AZ jab a couple of hours ago. Door to door in under 25 mins.
Lemoentjie
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So it sounds like the astrazeneca vaccine will be banned in Europe.

Haven't heard that Sputnik having any problems. Definitely seems to be the superior adenovirus vaccine.
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Saint
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Dinsdale Piranha wrote: Thu Mar 18, 2021 12:47 pm
Saint wrote: Thu Mar 18, 2021 12:23 pm In other good news, it looks like the Brazil variant is more susceptible to AZ and Pfizer than first thought - although not peer reviewed yet
I saw some analysis that said the initial reports were really pretty inaccurate - correct about the transmissibility but not about vaccine resistance - due to the people the analysis was based on - a similar issue to the SA variant reporting.

On another note the USA stockpiling AZ makes me think it will be approved pretty soon.

Got my first AZ jab a couple of hours ago. Door to door in under 25 mins.
They still haven't completed the US Phase III trials, then it will need to go to FDA. By the time it gets approved (if it does) they'll have piles of vaccine from other sources already
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Saint
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Marylandolorian wrote: Thu Mar 18, 2021 12:52 pm
Biffer wrote: Thu Mar 18, 2021 10:41 am
Rinkals wrote: Thu Mar 18, 2021 10:27 am I'm talking about a "temporary moratorium".

Not cancelling the right to earn from your investment.
So you're expecting China and India to 'forget' the IP and never use it again after a couple of years? That would not happen. It's fairyland to think it would.
It’s possible, not with the chinese of course.
from March 3rd

President Biden announced Tuesday that pharmaceutical giant Merck will help make Johnson & Johnson’s single-shot coronavirus vaccine — an unusual pact between fierce rivals that is among several steps intended to boost supply as Biden pushes toward having enough shots for every adult by the end of May.
Biden hailed the development as an example of industry coming together for the common good, in keeping with his frequent calls for a stronger emergency footing to combat the pandemic.
“Two of the largest pharmaceutical companies in the world who are usually competitors are working together on the vaccine,” he said in remarks delivered at the White House. “This is the type of collaboration between companies we saw in World War II.”

https://www.washingtonpost.com/health/2 ... rtnership/

Go Merica
Merck already have the knowhow to make an Adenovirus so there's no real knowledge transfer taking place
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Openside
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TheNatalShark wrote: Sun Mar 14, 2021 2:30 pm
Paddington Bear wrote: Sun Mar 14, 2021 2:26 pm
Saint wrote: Sun Mar 14, 2021 1:38 pm Ireland become the latest country to suspend the use of AZ based on what is effectively anecdotal evidence. Completely ignoring the data from now 17 million doses delivered with so signs at all of any increase in blood clotting events

Utterly bonkers
What is going on here? Political cover for delivery delays?
Those dirty Europeans in the central European country of Thailand are also using "suspending to investigate" as a smoke screen for their failure in the European procurement programme.


Fu.ck sakes the blinkers are incredible.
Do you realise this is against the advice of both WHO and the Erm EMA (hint the E stands for European...)
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Hong Kong
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TB63 wrote: Wed Mar 17, 2021 8:51 am
Enzedder wrote: Wed Mar 17, 2021 2:37 am
Hong Kong wrote: Wed Mar 17, 2021 1:09 am I’m getting the BioNTech vaccination: first on 31 March, 2nd on 21 April
Can I have your porn collection?
You've not got enough time left on this earth to go through them all..
🤣🤣🤣
Biffer
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EMA says AZ vaccine is safe and effective

https://www.bbc.co.uk/news/world-europe-56440139
And are there two g’s in Bugger Off?
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laurent
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Biffer wrote: Thu Mar 18, 2021 4:20 pm EMA says AZ vaccine is safe and effective

https://www.bbc.co.uk/news/world-europe-56440139
Well that's a surprise .

3 days lost at least and confidence Messed up for 1000s of people ...
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SaintK
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Well this should be lively. Given what he said about Hancock's department's Covid responses yesterday!
Catastrophically wrong eh?
[media] [/media]
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Lobby
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Had my first jab this afternoon. Oxford AstraZenaca. Whole process was really easy, and got the jab at my local pharmacy, just 10 minutes walk from my house.
dpedin
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Jabbed today in Embra - at the old RBS building at the Gyle. AZ vaccine. In and out in 15 mins including waiting to see if I died after the jab. Easy peasy!
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laurent
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dpedin wrote: Thu Mar 18, 2021 5:14 pm Jabbed today in Embra - at the old RBS building at the Gyle. AZ vaccine. In and out in 15 mins including waiting to see if I died after the jab. Easy peasy!
But is your 5G reception improved Now ?
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SaintK
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laurent wrote: Thu Mar 18, 2021 5:32 pm
dpedin wrote: Thu Mar 18, 2021 5:14 pm Jabbed today in Embra - at the old RBS building at the Gyle. AZ vaccine. In and out in 15 mins including waiting to see if I died after the jab. Easy peasy!
But is your 5G reception improved Now ?
No, but Bill Gates can now get directly in touch!
dpedin
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SaintK wrote: Thu Mar 18, 2021 5:44 pm
laurent wrote: Thu Mar 18, 2021 5:32 pm
dpedin wrote: Thu Mar 18, 2021 5:14 pm Jabbed today in Embra - at the old RBS building at the Gyle. AZ vaccine. In and out in 15 mins including waiting to see if I died after the jab. Easy peasy!
But is your 5G reception improved Now ?
No, but Bill Gates can now get directly in touch!
Funnily enough my new apple laptop arrived today. I must have got the apple jab.
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tabascoboy
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Slightly different focus in this link to the one given before
AstraZeneca: UK and EU clot reviews confirm safety of vaccine

There is no evidence the AstraZeneca Covid vaccine causes blood clots, say UK and EU regulators after a "thorough and careful review".

The MHRA and the EMA say people can have confidence in the vaccine's benefits and should get immunised, despite some countries pausing use.

But anyone with a headache lasting more than four days after vaccination should seek medical advice, as a precaution.

The same advice applies if someone develops unusual bruising.

That is because the regulators have received a very small number of reports of an extremely rare form of blood clot occurring in the brain.

It is this type of clot that triggered some European countries to pause rollout of the Oxford-AstraZeneca vaccine.

In the UK, five cases of cerebral sinus vein thrombosis (CSVT), among 11 million people who have received the vaccine, occurred in men aged between 19 and 59. One of these was fatal.

The EMA has received an additional 13 reports of CSVT.

CSVT can occur naturally and no link to the vaccine has been established. The patients also had low blood platelet counts - cells involved with clotting.

Covid infection can make clots more likely.

Dr June Raine, chief executive of the MHRA, said regulators would continue to closely monitor the situation and people should have the vaccine when it is their turn: "The public can have every confidence in the thoroughness of our review."
https://www.bbc.co.uk/news/health-56447367
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Raggs
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tabascoboy wrote: Thu Mar 18, 2021 6:32 pm Slightly different focus in this link to the one given before
AstraZeneca: UK and EU clot reviews confirm safety of vaccine

There is no evidence the AstraZeneca Covid vaccine causes blood clots, say UK and EU regulators after a "thorough and careful review".

The MHRA and the EMA say people can have confidence in the vaccine's benefits and should get immunised, despite some countries pausing use.

But anyone with a headache lasting more than four days after vaccination should seek medical advice, as a precaution.

The same advice applies if someone develops unusual bruising.

That is because the regulators have received a very small number of reports of an extremely rare form of blood clot occurring in the brain.

It is this type of clot that triggered some European countries to pause rollout of the Oxford-AstraZeneca vaccine.

In the UK, five cases of cerebral sinus vein thrombosis (CSVT), among 11 million people who have received the vaccine, occurred in men aged between 19 and 59. One of these was fatal.

The EMA has received an additional 13 reports of CSVT.

CSVT can occur naturally and no link to the vaccine has been established. The patients also had low blood platelet counts - cells involved with clotting.

Covid infection can make clots more likely.

Dr June Raine, chief executive of the MHRA, said regulators would continue to closely monitor the situation and people should have the vaccine when it is their turn: "The public can have every confidence in the thoroughness of our review."
https://www.bbc.co.uk/news/health-56447367
Isn't the actual rate indistinguishable from the normal rate though? At least I believe that I read that.
Give a man a fire and he'll be warm for a day. Set a man on fire and he'll be warm for the rest of his life.
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tabascoboy
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Well, just over 45% of over 18's in my constituency area now had the jab, mine is set for tomorrow...
Ovals
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Lemoentjie wrote: Thu Mar 18, 2021 1:53 pm So it sounds like the astrazeneca vaccine will be banned in Europe.

Haven't heard that Sputnik having any problems. Definitely seems to be the superior adenovirus vaccine.
Well, this post aged well :lol: :lol: :lol: :lol:
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tabascoboy
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Raggs wrote: Thu Mar 18, 2021 6:36 pm

Isn't the actual rate indistinguishable from the normal rate though? At least I believe that I read that.
If I read it correctly that is true for clots in general but:

"the vaccine is not associated with an increase in the overall risk of blood clots (thromboembolic events) in those who receive it"

"the vaccine may be associated with very rare cases of brain clots and clots in multiple blood vessels (known as disseminated intravascular coagulation or DIC - the EMA has received seven reports of this so far)"
Last edited by tabascoboy on Thu Mar 18, 2021 6:42 pm, edited 1 time in total.
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Raggs
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Ovals wrote: Thu Mar 18, 2021 6:38 pm
Lemoentjie wrote: Thu Mar 18, 2021 1:53 pm So it sounds like the astrazeneca vaccine will be banned in Europe.

Haven't heard that Sputnik having any problems. Definitely seems to be the superior adenovirus vaccine.
Well, this post aged well :lol: :lol: :lol: :lol:
Everyone else was just leaving that bait alone I believe. The idea of suggesting a vaccine that's not even got approval in Europe, is better than one that's been cleared in far more countries, and has agencies backing it, just seems odd.
Give a man a fire and he'll be warm for a day. Set a man on fire and he'll be warm for the rest of his life.
Ovals
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Raggs wrote: Thu Mar 18, 2021 6:42 pm
Ovals wrote: Thu Mar 18, 2021 6:38 pm
Lemoentjie wrote: Thu Mar 18, 2021 1:53 pm So it sounds like the astrazeneca vaccine will be banned in Europe.

Haven't heard that Sputnik having any problems. Definitely seems to be the superior adenovirus vaccine.
Well, this post aged well :lol: :lol: :lol: :lol:
Everyone else was just leaving that bait alone I believe. The idea of suggesting a vaccine that's not even got approval in Europe, is better than one that's been cleared in far more countries, and has agencies backing it, just seems odd.
Smells like Dozy............
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JM2K6
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SaintK wrote: Thu Mar 18, 2021 4:39 pm Well this should be lively. Given what he said about Hancock's department's Covid responses yesterday!
Catastrophically wrong eh?
[media] [/media]
(You don't need to use the media tags, Twitter URLs are converted automatically)

I do hope Cummings continues to brag about the neuroscientist (!?) he brought in who apparently had a big impact on our COVID response (?!?!?)
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laurent
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And lock down it is at last for Paris region the north and southern alps...

a bit late I think :(

they are not closing schools so I doubt it'll be very afficient
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tabascoboy
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Had my first jab this morning, the AZ variety.

EDIT: 2 hours later, arm feels just a little stiff but not so much as to stop normal activity
Last edited by tabascoboy on Fri Mar 19, 2021 11:36 am, edited 1 time in total.
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Saint
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First batch of Moderna arrives next month. That'll open the door for Group 10 then, so looks like I'll be getting that
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Lobby
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France start using the AZ vaccine again today, but having previously restricted its use to those under 65, for no good reason, and then suspending its use for no good reason, they are now restricting its use to those over 55, again for no good reason.

That’s sure to encourage uptake in Europe’s most vaccine-hesitant nation.

As some other wag has put it

Image
Dinsdale Piranha
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tabascoboy wrote: Fri Mar 19, 2021 10:13 am Had my first jab this morning, the AZ variety.

EDIT: 2 hours later, arm feels just a little stiff but not so much as to stop normal activity
I had my first jab yesterday morning. Felt a little achy late evening so dosed myself with beer and ibuprofen. Felt fine this morning and went out for a bike ride. YMMV.
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Sandstorm
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Dinsdale Piranha wrote: Fri Mar 19, 2021 2:33 pm
tabascoboy wrote: Fri Mar 19, 2021 10:13 am Had my first jab this morning, the AZ variety.

EDIT: 2 hours later, arm feels just a little stiff but not so much as to stop normal activity
I had my first jab yesterday morning. Felt a little achy late evening so dosed myself with beer and ibuprofen. Felt fine this morning and went out for a bike ride. YMMV.
Anecdotal evidence I have seen is that women seem to react worse than men to the AZ jab. Many birds have aches, upset tummy and feel flu-like the day after. Maybe HRT related?

My male friends have had virtually no symptoms.
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tabascoboy
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Lobby wrote: Fri Mar 19, 2021 1:15 pm France start using the AZ vaccine again today, but having previously restricted its use to those under 65, for no good reason, and then suspending its use for no good reason, they are now restricting its use to those over 55, again for no good reason.

That’s sure to encourage uptake in Europe’s most vaccine-hesitant nation.

As some other wag has put it

Image
Unfortunately we do have some pricks though, mostly in the Government and media...
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Saint
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Sandstorm wrote: Fri Mar 19, 2021 3:31 pm
Dinsdale Piranha wrote: Fri Mar 19, 2021 2:33 pm
tabascoboy wrote: Fri Mar 19, 2021 10:13 am Had my first jab this morning, the AZ variety.

EDIT: 2 hours later, arm feels just a little stiff but not so much as to stop normal activity
I had my first jab yesterday morning. Felt a little achy late evening so dosed myself with beer and ibuprofen. Felt fine this morning and went out for a bike ride. YMMV.
Anecdotal evidence I have seen is that women seem to react worse than men to the AZ jab. Many birds have aches, upset tummy and feel flu-like the day after. Maybe HRT related?

My male friends have had virtually no symptoms.
Mrs Saint reckons that locally the trend is that for first dose AZ makes you feel crap but second dose is no problem. Pfizer is the opposite; you don't notice dose 1, but dose 2 can be a killer.

On average of course
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Lobby
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Dinsdale Piranha wrote: Fri Mar 19, 2021 2:33 pm
tabascoboy wrote: Fri Mar 19, 2021 10:13 am Had my first jab this morning, the AZ variety.

EDIT: 2 hours later, arm feels just a little stiff but not so much as to stop normal activity
I had my first jab yesterday morning. Felt a little achy late evening so dosed myself with beer and ibuprofen. Felt fine this morning and went out for a bike ride. YMMV.
Had my jab yesterday. My neck and shoulders feel a bit stiff today, and have a very mild headache, but that’s it.
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fishfoodie
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Lobby wrote: Fri Mar 19, 2021 1:15 pm France start using the AZ vaccine again today, but having previously restricted its use to those under 65, for no good reason
I don't know if this has been corrected before; but your statement is arse about face.

I was just listening to the head of the Irish medicines board explain the logic; & it isn't a case of the AZ being restricted to the under 65s; it's a decision to prioritize the mRNA vaccines to the most, "at risk"; i.e. the over 65s !

When there are more supplies of vaccine, I'm sure they'll remove the restriction; but right now with the supply issues, they're fully focused on getting coverage to the most at risk.
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Lobby
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Dinsdale Piranha wrote: Fri Mar 19, 2021 2:33 pm
tabascoboy wrote: Fri Mar 19, 2021 10:13 am Had my first jab this morning, the AZ variety.

EDIT: 2 hours later, arm feels just a little stiff but not so much as to stop normal activity
I had my first jab yesterday morning. Felt a little achy late evening so dosed myself with beer and ibuprofen. Felt fine this morning and went out for a bike ride. YMMV.
Had my jab yesterday. My neck and shoulders feel a bit stiff today, and have a very mild headache, but that’s it.
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Saint
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660,276 doses delivered yesterday - 528,260 first doses, 132,016 second doses
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Lobby
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fishfoodie wrote: Fri Mar 19, 2021 3:57 pm
Lobby wrote: Fri Mar 19, 2021 1:15 pm France start using the AZ vaccine again today, but having previously restricted its use to those under 65, for no good reason
I don't know if this has been corrected before; but your statement is arse about face.

I was just listening to the head of the Irish medicines board explain the logic; & it isn't a case of the AZ being restricted to the under 65s; it's a decision to prioritize the mRNA vaccines to the most, "at risk"; i.e. the over 65s !

When there are more supplies of vaccine, I'm sure they'll remove the restriction; but right now with the supply issues, they're fully focused on getting coverage to the most at risk.
I’m not sure you have understood my post. When the AZ vaccine was first approved by the EMA for all adults, the French authorities restricted its use to those under 65 on the grounds that there was limited information on efficacy for this age group. This restriction was only lifted earlier this month. Then, when there was a scare about blood clots, France and several other countries halted its use altogether, despite the EMA saying it was safe and should continue to be used.

The AZ vaccine is being used again from today, but now with a new caveat from France’s health authorities that it is recommended only for those over 55, apparently on the basis that the blood clotting incidents occurred in people under 55. The EMA continues to recommend its use for all adults.

If the logic for now restricting its use to those over 55 is to prioritise the most at risk, that would be fine, but that isn’t what has been reported elsewhere.
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laurent
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Lobby wrote: Fri Mar 19, 2021 4:17 pm
fishfoodie wrote: Fri Mar 19, 2021 3:57 pm
Lobby wrote: Fri Mar 19, 2021 1:15 pm France start using the AZ vaccine again today, but having previously restricted its use to those under 65, for no good reason
I don't know if this has been corrected before; but your statement is arse about face.

I was just listening to the head of the Irish medicines board explain the logic; & it isn't a case of the AZ being restricted to the under 65s; it's a decision to prioritize the mRNA vaccines to the most, "at risk"; i.e. the over 65s !

When there are more supplies of vaccine, I'm sure they'll remove the restriction; but right now with the supply issues, they're fully focused on getting coverage to the most at risk.
I’m not sure you have understood my post. When the AZ vaccine was first approved by the EMA for all adults, the French authorities restricted its use to those under 65 on the grounds that there was limited information on efficacy for this age group. This restriction was only lifted earlier this month. Then, when there was a scare about blood clots, France and several other countries halted its use altogether, despite the EMA saying it was safe and should continue to be used.

The AZ vaccine is being used again from today, but now with a new caveat from France’s health authorities that it is recommended only for those over 55, apparently on the basis that the blood clotting incidents occurred in people under 55. The EMA continues to recommend its use for all adults.

If the logic for now restricting its use to those over 55 is to prioritise the most at risk, that would be fine, but that isn’t what has been reported elsewhere.
Official reason is all the blood clotting cases were under 55.

there is no valid reason to restrict however AZ is unable to provide more than a 3rd of contracted vaccine. (there was a dip in vaccination this week thanks to the stupid reaction by the German government (funnily the Swedes appear to have suspended vaccination with AZ too..
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Grandpa
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Sandstorm wrote: Fri Mar 19, 2021 3:31 pm
Dinsdale Piranha wrote: Fri Mar 19, 2021 2:33 pm
tabascoboy wrote: Fri Mar 19, 2021 10:13 am Had my first jab this morning, the AZ variety.

EDIT: 2 hours later, arm feels just a little stiff but not so much as to stop normal activity
I had my first jab yesterday morning. Felt a little achy late evening so dosed myself with beer and ibuprofen. Felt fine this morning and went out for a bike ride. YMMV.
Anecdotal evidence I have seen is that women seem to react worse than men to the AZ jab. Many birds have aches, upset tummy and feel flu-like the day after. Maybe HRT related?

My male friends have had virtually no symptoms.
I was very ill after the AZ vaccine. My sister and mother were unaffected... two male mates were also badly affected... apparently the older you are, the less side effects...

Vaccine side effects: My experience of them and what they mean - https://www.bbc.co.uk/news/health-56375307
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